In order to determine if LARP7 has the same functions in vivo with regard to telomere maintenance, we performed telomere length analysis in lymphocyte DNA extracted from humans with Alazami syndrome, both the cohort originally described [21] as well as in a Canadian family with a single affected individual (8 years old) and two parents that were carriers for a distinct loss-of-function mutation in LARP7 (a one-nucleotide deletion which causes a frameshift and premature stop, c.756_757del, p.Arg253Ile*6). Here, LARP7 is linked to microcephalic primordial dwarfism, Alazami type.