ERBB2 and renal cell carcinoma: We found over expression of CCND1 playing important role in regulation of Wnt/β-catenin signaling along with other cancer related pathways like Acute Myeloid Leukemia Signaling, Non-Small Cell Lung Cancer Signaling, PTEN Signaling, Regulation of Cellular Mechanics by Calpain Protease, ErbB2-ErbB3 Signaling, HER-2 Signaling in Breast Cancer, HER-2 Signaling in Breast Cancer, Thyroid Cancer Signaling, Endometrial Cancer Signaling etc. Further extensive molecular pathway analysis may help to better understand the mechanism of RCC initiation, invasion and metastasis.