However, now it is much clearer that structural alterations are found in ion channelopathies; for example, myocardial fibrosis is observed in BrS [24], [25], [26], DCM and non-compaction cardiomyopathy features are found in cardiac ryanodine receptor 2 mutation that is classically observed in CPVT [27]. This evidence concerns the gene RYR2 and catecholaminergic polymorphic ventricular tachycardia.