Ectopic miR-34a expression with miR-34a mimic decreased the invasion and proliferation of Hela and Siha cells (Supplementary Fig. S2a,b) and led to the upregulation of E-cadherin and downregulation of the known miR-34a targets Survivin and Snail as well as Vimentin (Supplementary Fig. S2c,d), demonstrating that iASPP might exert its oncogenic effects through the regulation of tumor suppressive mR-34a in CC cells. This evidence concerns the gene BIRC5 and neoplasm.