In general, the histopathological diagnosis of adrenal tumors relies on a panel of different parameters: For the determination of the adrenocortical origin, the expression of SF-1 has emerged as the most valid marker [19] while for the discrimination of benign from malignant adrenocortical tumors the Ki67 index is of high importance. Here, MKI67 is linked to adrenal gland neoplasm.