27 Liakou Liakou CI CI Kamat Kamat A A Tang Tang DN DN Chen Chen H H Sun Sun J J Troncoso Troncoso P P Logothetis Logothetis C C Sharma Sharma P P CTLA-4 blockade increases IFNγ-producing CD4; ICOShi cells to shift the ratio of effector to regulatory T cells in cancer patients CTLA-4 blockade increases IFNγ-producing CD4; ICOShi cells to shift the ratio of effector to regulatory T cells in cancer patients Proc Natl Acad Sci USA Proc Natl Acad Sci USA 2008 2008 105 105 14987 14987 92 92 18818309 18818309. The gene discussed is IFNG; the disease is cancer.