27 Liakou Liakou CI CI Kamat Kamat A A Tang Tang DN DN Chen Chen H H Sun Sun J J Troncoso Troncoso P P Logothetis Logothetis C C Sharma Sharma P P CTLA-4 blockade increases IFNγ-producing CD4; ICOShi cells to shift the ratio of effector to regulatory T cells in cancer patients CTLA-4 blockade increases IFNγ-producing CD4; ICOShi cells to shift the ratio of effector to regulatory T cells in cancer patients Proc Natl Acad Sci USA Proc Natl Acad Sci USA 2008 2008 105 105 14987 14987 92 92 18818309 18818309. This evidence concerns the gene CD4 and cancer.