In order to examine the role of differentiation-inducing miRNAs in regulating MYCN expression in neuroblastoma cells, we overexpressed a group of thirteen differentiation-inducing miRNAs that we identified previously [14] using miRNA mimics, synthetic oligonucleotides (oligos) used to raise intracellular miRNA levels, in a neuroblastoma cell line BE(2)-C, the cell line that we used to identify the differentiation-inducing miRNAs through high-content screening [14]. The gene discussed is MYCN; the disease is neuroblastoma.