In addition to IL-6, other cytokines and/or chemokines also contribute to the cross-talk between stroma and MM cells including IL-8, RANTES (regulated and normal T cell expressed and secreted), IL-1β, TNF-α, IGF-1 (insulin-like growth factor-1) and others [6]. The gene discussed is CXCL8; the disease is Miyoshi myopathy.