The Type I that arises by precursor lesion and includes neoplasms that are commonly indolent, genetically stable and characterized by poor response to platinum-based chemotherapy; the Type II, characterized by de novo lesions, includes high-grade tumors that are usually diagnosed in advanced stages and are genetically unstable: frequently TP53 mutated, carry wild-type RAS genes and often germline or sporadic BRCA1/2 mutations or BRCA1/2 promoter methylation [12]. Here, BRCA1 is linked to neoplasm.