Cav-1 immunoreactivity in prostate tumor stroma was weakly inversely correlated with GS, metastasis, tumor size, local tumor stage, tumor cell proliferation, tumor stroma hyaluronan, tumor vascular density and tumor epithelial pEGFR expression, and weakly positively correlated with non-malignant stroma Cav-1 immunoreactivity and tumor stroma androgen receptor expression (Table 1). The gene discussed is CAV1; the disease is neoplasm.