Cav-1 immunoreactivity in prostate tumor stroma was weakly inversely correlated with GS, metastasis, tumor size, local tumor stage, tumor cell proliferation, tumor stroma hyaluronan, tumor vascular density and tumor epithelial pEGFR expression, and weakly positively correlated with non-malignant stroma Cav-1 immunoreactivity and tumor stroma androgen receptor expression (Table 1). This evidence concerns the gene CAV1 and prostate neoplasm.