As shown in Figure 2C,D RACK1-siRNAs could decrease RACK1 expression effectively in glioblastoma cells in U87 and U251 cells, respectively, as compared with NC groups (Figure 2C *** p < 0.01, *** p < 0.01 for U87; Figure 2D *** p < 0.01,*** p < 0.01 for U251). The gene discussed is RACK1; the disease is glioblastoma.