The expression of RACK1 was 3.33% (7/211) for grade I, 12.87% (22/171) for grade II, 30.19% (48/159) for grade III, and 51.89% (96/185) for grade IV glioma tissues, as shown in Figure 1D, indicating that the RACK1 protein was greatly up-regulated in high grade compared with the corresponding low grade glioma tissues. Here, RACK1 is linked to central nervous system cancer.