The results demonstrated that knockdown of RACK1 led to a dramatic accumulation of cells in G0/G1 phase (* p < 0.05 for U87; * p < 0.05 for U251), while obviously reduced their proportions at the S phase in comparison with NC groups both in U87 and U251 cells (Figure 4A,B), implying the potential acceleration of the cell cycle for glioma by high RACK1 levels. The gene discussed is RACK1; the disease is glioma.