To conclude: (1) increases of Day 7 GFAP levels (above 11.14 ng/mL) and Day 7 IL-6 serum levels (above 71.26 pg/mL) may predict worse outcome; (2) plasma GFAP, tau and Aβ42 may be increased up to 90 days after moderate to severe and even mTBI. The gene discussed is GFAP; the disease is concussion.