In addition to establishing that TNF-α/IL-10 ratio is inversely correlated with burn injury severity measures of TBSA, inhalation injury status, APACHEII, Baux, R-Baux, Ryan, and ABSI scores, we found that it is a biomarker that predicts increased risk of hypersusceptibility to infection during the course of recovery. The gene discussed is IL10; the disease is infection.