This finding is supported by previous OSIC-flow data in SJS-TEN patients31 (who have an OcMMP-like conjunctival scarring phenotype), and tear ELISA analysis, where neutrophil collagenase matrix metalloproteinase (MMP)-8 and -9 together with myeloperoxidase have been detected in patients with both SJS-TEN and OcMMP.38 Most importantly, our novel finding demonstrates that eyes with an increase in conjunctival epithelial neutrophils at baseline had evidence of fornix shrinkage at 12 months follow-up. Here, MMP8 is linked to toxic epidermal necrolysis.