SNAI2 and neuroblastoma: SNAI2 is regarded as a cancer promoter factor due to the following facts: SNAI2 promotes survival through suppression of apoptosis and drives EMT transition and metastasis, [7, 18–20]; SNAI2 blocks TKI-induced apoptosis in myeloid leukemia, lung cancer and neuroblastoma cells [21–23]; SNAI2 has been shown to drive lung metastasis of immortalized and transformed melanocytic Mel-STR cells [7].