Chiewsilp et al. also reported a negative relationship for HLA-B*13 with dengue shock syndrome (DSS) and/ or dengue hemorrhagic fever (DHF)[26].These studies suggested that B*13 allele and haplotype A*30-B*13-C*06 is a protective factor against AIDS and hepatitis B, respectively. Here, HLA-B is linked to hepatitis B virus infection.