Accordingly, when we overexpressed LATS1, we were able to revert MG effects on YAP accumulation as assessed by immunofluorescence using two anti-YAP antibodies in MDA-MB-231 cells (Figure 6C and Figure 6—figure supplement 1B), and in the other breast cancer cell lines analyzed (Figure 6—figure supplement 1C and D). The gene discussed is LATS1; the disease is breast carcinoma.