We therefore investigated the ability of BSP to inhibit the clonogenic growth and proliferation of two acute myeloid leukemia (AML) cell lines (MV4;11 and KASUMI-1), the hyperdiploid AML line OCI-AML3, and the BCR-ABL–positive chronic myeloid leukemia (CML) cell line K562, and we observed growth inhibition in the concentration range 100 to 500 nM (Fig. 3A and fig. This evidence concerns the gene BCR and acute myeloid leukemia.