For hexokinase II (HKII) JTK_CYCLE indicated rhythmicity in sedentary lean and tendencies in obese and type 2 diabetic donors (Fig. 3, UL p < 0.05; OB p = 0.07; T2D p = 0.09, TL p = 1.00); However, one-way ANOVA revealed no significant differences in HKII gene expression in time in sedentary lean (p > 0.05). The gene discussed is HK2; the disease is type 2 diabetes mellitus.