CACNA1I and schizophrenia: We did not identify a phenotype associated with T797M in our assays of CaV3.3 function and, as discussed above, we cannot rule out the possibility that T797M will be disruptive to CaV3.3 signaling in the native environment, but our analyses should help guide future studies designed to assess the potential contribution of R1346H-CaV3.3 to schizophrenia risk.