NS1 (30μM) strongly reduced the viability of multiple melanoma cells, SK-Mel28, which carried mutations of p53 and of BRAF, 1205 Lu cells mutated in BRAF and PTEN and melanoma cells freshly isolated from a patient at 72h without affecting the viability of healthy melanocytes (NHM) (Figure 1A). This evidence concerns the gene BRAF and melanoma.