Although EGFR has been largely reported in the field of cancer because of its involvement in cell proliferation, migration, and invasion [20, 21], an increasing number of studies have supported its diverse roles in pathogenic bacterial infections, including Haemophilus influenza, Klebsiella pneumonia, Neisseria gonorrhoeae, Pseudomonas aeruginosa, and Helicobacter pylori infections [14, 22–24]. This evidence concerns the gene EGFR and bacterial infectious disease.