However, while there have been some previous metabolomics studies on the comparison between platinum-sensitive and resistant ovarian cancer cell lines [3], and between effects of nicotinamide phosphoribosyltransferase on ovarian and colorectal cancers [33], this is the first metabolomics-based study to evaluate the effects of melittin on human ovarian cancer cell lines as a potential anticancer therapeutic agent. This evidence concerns the gene NAMPT and colorectal cancer.