Interestingly, expression of efflux transporters of the ABC superfamily (ABCC1, ABCC3-6, ABCB1, ABCG2) increased with NAFLD progression from steatosis to NASH, whereas reduced glycosylation of MRP2 (encoded by ABCC2) resulted in reduced functional levels of this transporter at the apical plasma membrane [182]. Here, ABCC2 is linked to metabolic dysfunction-associated steatohepatitis.