Up-to-date, eight publications have found a positive association between increased densities of DC-Lamp+ DCs and prognosis, in several types of tumors, including NSCLC (1, 2, 9), melanoma (20), renal cell carcinoma [RCC (24)], breast (11), and colorectal cancer (15) (Table 1 and Figure 1). Here, LAMP3 is linked to renal cell carcinoma.