CALR and rheumatoid arthritis: For example, autoreactive plasma cells release autoantibodies, such as anti-citrullinated protein antibodies (ACPA/anti-CCP) in rheumatoid arthritis (7); antibodies targeting ribonucleoproteins Ro (Sjögren’s syndrome antigen A; SSA) and La (Sjögren’s syndrome antigen B; SSB) in Sjögren’s syndrome (98); anti-thyroglobulin and thyroperoxidase antibodies in Hashimoto’s thyroiditis (99); and nicotinic acetylcholine receptor-specific antibodies in myasthenia gravis (100).