Both SRRT and SLC12A9 were down-regulated in T2D (SRRT: log2fold -0.87; adjusted p: 4.46E-5; SLC12A9 log2fold: -0.76; adjusted p: 5.87E-4) with replication in our independent cohort (Fig. 5B). This evidence concerns the gene SRRT and type 2 diabetes mellitus.