Evaluation of serum anti-p53 Ab level and PET parameters showed that there was no significant correlation between serum anti-p53 Ab level and SUVmax, SUVave, TLG, tumor volume, and tumor size of patients with lung cancer (p=0.189, 0.123, 0.572, 0.928, 0.421, respectively). This evidence concerns the gene TP53 and lung cancer.