The here identified ubiquitination-deubiquitination assisted-folding cycle also appears to operate on other membrane proteins such as CFTR or the anthrax toxin receptor 2 (also know as Capillary Morphogenesis gene 2, CMG2), loss of function of which leads to Hyaline Fibromatosis Syndrome (Deuquet et al., 2012). The gene discussed is ANTXR2; the disease is hyaline fibromatosis syndrome.