As predictive markers in patients with HCC, tumor markers including those for alpha‐fetoprotein (AFP), Lens culinaris agglutinin‐reactive fraction of AFP (AFP‐L3), and des‐gamma‐carboxy prothrombin (DCP) have been reported in many past studies 10, 11, 12, 13, 14. This evidence concerns the gene AFP and hepatocellular carcinoma.