TNF and rheumatoid arthritis: In this exploratory analysis of RA patients who discontinued an anti-TNF agent as their first bDMARD, patients receiving agents with other MOA rather than another anti-TNF as their second or third bDMARD were more than twice as likely to achieve a good or a good or moderate RAPID3 response at 6 months after adjusting for patient demographics, seropositivity, and baseline RAPID3 score.