TP53INP1, SIRT1, and EGR1, regulators of p53 transcriptional activity, have also been shown to be direct targets of apoptomiRs- miR-155, miR-34, and miR-191, respectively, in breast cancer (Li et al., 2013; Nagpal et al., 2013; Zhang et al., 2013). The gene discussed is TP53; the disease is breast cancer.