CASR and familial hypocalciuric hypercalcemia: Recent studies by Nesbit et al. and Rogers et al. revealed that disorders with FHH or ADH phenotype can be associated with mutations on partner proteins associated with CaSR-mediated signaling, for instance the loss-of-function mutations of the sigma subunit of adaptor protein-2 (AP2) and mutations on G-protein subunit-α11 (GNA11), (Nesbit et al., 2013; Rogers et al., 2014).