Fibronectin mRNA was increased in children with STRA compared with controls without asthma when cells were stimulated with IL-17A alone (P = .02; Fig E5, B), while collagen I was increased in children with STRA compared with controls without asthma when cells were stimulated with IL-22 (P = .02), IL-17 (P = .005), or IL-17 with budesonide (P = .05) (Fig E5, C). Here, IL22 is linked to asthma.