NR1H3 and pulmonary fibrosis: We showed previously that miR-155−/− mice have higher serum cholesterol concentrations while on a high fat diet22; therefore, to test whether different oxysterol concentrations in miR-155−/− mice treated with bleomycin were responsible for the Lxra activation and exacerbated lung fibrosis, we profiled serum oxysterols using mass spectrometry (Table E3).