As shown in Table 4, there are only three studies involving the analysis of the entire coding region of the BRCA1/BRCA2: the study published by Carraro and colleagues in 2013 [24] that examined 54 women with BC diagnosed before the age of 35, the study published by Silva et al. in 2014 [23] which included 120 women and ours, that analyzed 349 index cases of suspected HBOC families. Here, BRCA2 is linked to breast cancer.