SENP1 and nonpapillary renal cell carcinoma: We quantified SENP1 mRNA in the 36 pairs of ccRCC tumors (T) and adjacent normal tissues (N), and divided the tumor samples into SENP1 high-expression and low-expression groups according to the log2 value of the ratio of T/N SENP1 mRNA level for each pair (Figure 1C).