In addition, single nucleotide polymorphisms (SNPs) in CDKN2BAS are associated with the risk of multiple diseases, including comprising CHD [7, 9, 11], myocardial infarction [7], type 2 diabetes [12], ischemic stroke [13], and periodontitis [14]. The gene discussed is CDKN2B-AS1; the disease is coronary artery disorder.