In conclusion, our results suggest that, in a Chinese Han population, rs10757274 in CDKN2BAS is associated with the risk of CHD both in men and women, rs7865618 is correlated with an increased risk of CHD only in women, and the haplotype AA (rs10757274 and rs1333042) of CDKN2BAS is associated with a decreased CHD risk in men. The gene discussed is CDKN2B-AS1; the disease is coronary artery disorder.