PLK4 and bacterial infectious disease with sepsis: As shown in S1 Fig, φSa3 (OC8) had the immune evasion cluster (IEC) with the immune evasion genes scn (for staphylococcal complement inhibitor, SCIN) and sak (for staphylokinase, SAK) and also the SAg gene sea, on the left-end side, similar to ST239/SCCmecIII HA-MRSA TW20, which was isolated from a case of intensive care unit (ICU)-associated bacteremia in London [50,51].