Renal abnormalities are seen in 10% to 60% and proteinuria is reported in 15% to 18% of the cases of Kimura disease.[2,18,19] Renal lesions, including membranous nephropathy, mesangial proliferative glomerulonephritis, and minimal change disease, typically appear months or even years after lymph node enlargement or development of subcutaneous nodules.[3,20–22] In adults, membranous nephropathy is predominant and immunofluorescent microscopy mainly shows deposition of IgG and C3 and occasionally IgM and IgA, mostly in the capillary loop and less frequently in the mesangium. The gene discussed is CD40LG; the disease is lipoid nephrosis.