To determine whether PAK inhibition could promote cell death in these cells, we calculated the percentage of apoptotic cells in HCC1419, BT-474, MDA-MB-361 and SK-BR-3 breast cancer cells treated with vehicle, PF-3758309 or transfected with PAK1 targeting siRNAs and incubated with cisplatin. Here, PAK1 is linked to breast carcinoma.