It has been shown recently that secretome collected from ADMSC cultured under less than 5% O2 contains high levels of granulocyte-macrophage-colony-stimulating factor (GM-CSF), vascular endothelial growth factor (VEGF), Interleukin-6 (IL-6), and insulin-like growth factor 1 (IGF-1)27 and was also found to be able to protect myocardial infarct in rat28. The gene discussed is CSF2; the disease is myocardial infarction.