It has to be pointed out that we have not applied the Bonferroni corrected P value in analyses of the CASR association with 8 main phenotypes tested in this study (nephrolithiasis-related ESRD, Ca, P, ALP, PTH, response to treatment with cinacalcet, prevalence of coronary artery disease, and survival probability). The gene discussed is PTH; the disease is nephrolithiasis.