Among polymorphic variants of cytokine-associated genes tested in HD patients (Supplementary Table 9), borderline associations with nephrolithiasis-related ESRD were shown for the chemokine (C-C motif) ligand 2 gene (CCL2 -2518 A > G) rs1024611 (Ptrend = 0.059) and the interleukin (IL) 18 gene (IL18) rs360719 (Ptrend = 0.085). The gene discussed is CCL2; the disease is Huntington disease.