Comparisons of clinical and laboratory data of HD patients stratified by CASR rs7652589 genotypes suggested the possibility of associations (P < 0.05 without the Bonferroni correction) between CASR rs7652589 SNP and patient age at the start of RRT, nephrolithiasis-related ESRD, serum total Ca concentration, and prevalence of PTH results over 500 pg/ml (Supplementary Table 3). The gene discussed is CASR; the disease is nephrolithiasis.