To further understand the influence of NSCLC driver mutations (EGFR/non-EGFR) on the lipidomic profile, we performed a combination of Mann-Whitney U test, OPLS-DA analysis and ROC analyses to identify lipid species that discriminated the EGFR mutants from the non-EGFR mutants (Table 3). Here, EGFR is linked to non-small cell lung carcinoma.