Compared with the NGT group, subjects in the pre-DM and nT2DM group exhibited higher levels of HOMA-IR, WHR, TG, γ-GGT, and IL-6, while the levels of HDL-C in the NGT group were higher than those of the pre-DM and nT2DM group (all P < 0.05). The gene discussed is IL6; the disease is diabetes mellitus.