This is a paradoxical finding, as classical psoriasis is known to respond to these agents.<h4>Purpose</h4>The clinical features of anti-TNF-α-induced psoriatic dermatitis are described.<h4>Method</h4>A 60-year-old man with Crohn's disease treated with infliximab, who developed anti-TNF-α-induced psoriasiform dermatitis, is described.<h4>Results</h4>The man developed erythematous skin lesions in the bilateral axillae two years after beginning infliximab treatment for Crohn's disease. This evidence concerns the gene TNF and psoriasis.