Analysis of the TCF7L2 rs1225404 polymorphism revealed a significant difference in tumor size between patients with the CT genotype, or CT and CC genotypes compared with the TT genotype, independent of other clinical and pathological data (Figure 1, CT: OR = 1.72, P = 0.02; CT + CC: OR = 1.71, P = 0.02). Here, TCF7L2 is linked to neoplasm.