Mutations in its paralog, ARID1B, are less frequent but have also been observed in melanoma, gastric cancer, colorectal cancer, HCC, neuroblastoma, and pancreatic cancer (Fujimoto et al. 2012; Khursheed et al. 2013; Sausen et al. 2013; Lee et al. 2015). The gene discussed is ARID1B; the disease is hepatocellular carcinoma.