Further to assess dynamic changes in expression of RA‐target genes in cultured AML specimen, we found that similar to those in normal cells (see Fig 1B), Am80‐GCSF induced significantly higher transcription of RA‐target genes compared to Am80 in both early and late differentiation induction stages (Fig 2Bi, day 2, day 6). Here, CSF3 is linked to acute myeloid leukemia.