NFATC4 and familial dilated cardiomyopathy: NFAT is also a criticalregulator of cardiac development and myocyte maturation (28), and the translocation of dephosphorylated NFAT-3 tonucleus in DCM can activate the calcineurin signaling pathway (29), whose activation can induce atrial hypertrophy during atrialfibrillation (30).